Saturday, March 28, 2009
In case you were wondering
DYF399 recLOH explanation by Rebekah
Referring to this map.
In between P2 and P3 is a copy of DYF399 that is a t type with a g insertion. I think that is your 27.1t value. On P1 are two copies of DYF399. One is a t type and the other a c type. Those would be your 22t and 22c. On P1 DYF399 is located between the 188bp copies of DYF408 and the two c type copies of DYS464.
Now the interesting thing is when the alternative configuration is mapped, that is when P1/P2 crossovers happen, the t type with a g insertion and c type are next to each other. If you then have a doubling of one of those values you are likely to have recLOH from a P1/P2 crossover. From this I think that DYF399 is a good way to tell how a recLOH happened.